i-Particles® technology originates from the fundamental statement that pharmaceuticals should never involve harmful by-products and only focus on patient safety. Starting from this idea, Adjuvatis technology is led by one main concept: safe-by-design.
Synthetized by an eco-friendly and surfactant-free process, i-Particles® exclusively consist in a biodegradable polymer and selected active pharmaceutical ingredients.
Increasing pharmaceutical efficacy and safety, extending product life cycle while reducing risk profile and costs.
Following 20 years of research and supported by a multi-skilled team, Adjuvatis will push forward your active’s intrinsic properties and potentiate your product development.
i-LipoP® for mRNA vectorization
Based on emergence of Covid-19 vaccines, i-LipoP® technology makes possible vectorization of various nucleic acids, especially mRNA.
i-LipoP® consists in i-Particles® covered by a lipidic bilayer, allowing nucleic acid adsorption.
i-Particles® in the core of the carrier system act as a solid spherical support and enable stabilization of the membrane, controling the structural morphology and improving reproducibility of formulations.
A lipidic bilayer covers the whole surface of the carrier, mimicrying a membrane environment. Hydrophobic compounds may be entrapped into the bilayer while hydrophilic ones are adsorbed on the surface, making possible the vectorization of nucleic acids such as mRNA.
Driver of innovation
i-Particles® and i-LipoP®-based formulations have demonstrated enhancements in healthcare and technological fields, especially vaccines, drug delivery and diagnostic. Adjuvatis is constantly extending the scope of applications to reach new markets and prove once again the versatility of its technology.
i-Particles® & i-LipoP®-based products and custom formulation service
Adjuvatis provides a catalog of products for plain, active and dyed i-Particles® and i-LipoP®, and a full formulation and characterization services in a rigorous quality framework.
What are you waiting for?
Discover our fully dedicated ways of working, integrating both skills and experience to provide cutting-edge service for formulation development of biopharmaceuticals.
Adjuvatis manufactures and formulates safe-by-design delivery systems called i-Particles® & i-LipoP® and proposes a custom formulation service for your biomolecule.
Our dynamic team, supported by a referent advisory board and external experts, qualified in Chemistry, Biochemistry and Biology, Manufacturing and Partnering. By working collaboratively, we are committed to innovate for your therapeutic product development.
Welcome in Lyon
At the heart of the Bioparc Lyon, a hotspot for biotechs and labs in Life Sciences in vicinity to institutional, academic and private companies, Adjuvatis benefits from a unique environment in terms of technological innovation.